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Paolo-Manzoni-image
MD, PhD
Paolo Manzoni


Paolo-Manzoni-image
MD, PhD
Paolo Manzoni


“"Inspired by nature, we now know that the model of human milk is the most perfect one. The more we try to mimic its composition, the closer we get to obtain at least a piece of the incredibly valuable health benefits that human milk delivers. "“
- Paolo Manzoni
My Mission

Dr. Manzoni’s primary research interests include pediatric and neonatal infectious diseases, fungal infections and prevention, human milk bioactive nutrients, RSV related diseases, retinopathy of prematurity, and neonatal nutrition.

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Recent Posts
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How To Cope With Colic
Few things are certain in life. Unfortunately, one of them is your infant having gut pain in the first weeks of life–otherwise known as colic. All those who are (or have been) happy parents of a wonderful newborn know that gastrointestinal colic (translation: frequent crying, fussing, and irritability) are almost unavoidable during the first 2-3 months of life. So, how can we cope with colic? Infantile colic has a number of causes, like constipation or slow-moving gas. But while they're inevitable, they don't have to be long-lasting. Colic is destined to resolve over time (usually within 3 months of age), but there are still things that you can do to ease the pain: Get empowered in managing colic by using simple actions, like massaging your infant when they're crying or “burping” after the end of a meal. Provide probiotics. These beneficial microorganisms are actually abundant in human breast milk and deliver a number of functions, including stool softening, increased bowel movement, and the establishment of a healthy gut! Several well-designed and reliable studies support that probiotics (like L.reuterii) are a safe and potentially beneficial option for the management of colic, especially when human fresh milk is not available.


Overshare
Lactoferrin 101
Did you ever wonder if there’s a link bridging together survival from the first hours of life, be it newborn babies, calfs, or lambs, or even rats? This link is Lactoferrin – the “magic” compound in mammals’ milk that protects all newborns from deadly infections soon after birth, once the “maternal womb shield” is no more active.  Lactoferrin is very abundant in colostrum (the milk produced in the first days), and remains highly represented in breastmilk in the weeks and months that follow—providing a natural defense against microbes and pathogens to all breastfed infants during those first critical months of life. For non-breastfed babies, the way to ensure they get lactoferrin in their diet is to supplement either through formula or through specific lactoferrin oral supplements. We know from several reliable studies that supplementation with lactoferrin significantly improves the outcomes of babies (who are not receiving it through breast milk), and that (conversely) babies receiving less lactoferrin than a certain threshold have significantly more infections than others. Not only this, but we also know that these benefits might last until possibly one year of age. Inspired by nature,mwe the more we try to mimic breast milk's composition, the closer we get to obtain at least a piece of the incredibly valuable health benefits that it delivers. Mimicking the model of Lactoferrin delivery to newborn babies and infants is certainly a way to narrow the gap between the perfection of nature, and the solutions that we have to provide when nature cannot be there.
#breastmilk.#lactoferrin.#protein.#formula.#nutrition.#science